911 research outputs found

    Subplate in a rat model of preterm hypoxia-ischemia.

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    OBJECTIVE: Hypoxia-ischemia (HI) in preterm infants primarily leads to injuries in the cerebral white matter. However, there is growing evidence that perinatal injury in preterms can also involve other zones including the cortical gray matter. In a neonatal rat model of HI, selective vulnerability of subplate has been suggested using BrdU birth-dating methods. In this study, we aimed to investigate the neuropathological changes of the subplate and deep layers of the cortex following cerebral HI in neonatal rats with specific cell markers. METHODS: P2 rats underwent permanent occlusion of the right common carotid artery followed by a period of hypoxia. P8 rats were analyzed using immunohistochemistry; subplate and deep layers cells were quantified and compared with sham-operated case. RESULTS: A large variability in the extent of the cerebral injury was apparent. For the three analyzed subplate populations (Nurr1+, Cplx3+, and Ctgf+ cells), no significant cell reduction was observed in mild and moderate cases. Only in severe cases, subplate cells were strongly affected, but these injuries were always accompanied by the cell reductions in layers VI and V. INTERPRETATION: We could therefore not confirm a specific vulnerability of subplate cells compared to other deep layers or the white matter in our model

    Dusty Cometary Globules in W5

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    We report the discovery of four dusty cometary tails around low mass stars in two young clusters belonging to the W5 star forming region. Fits to the observed emission profiles from 24 micron observations with the Spitzer Space Telescope give tail lifetimes < 30 Myr, but more likely < 5 Myr. This result suggests that the cometary phase is a short lived phenomenon, occurring after photoevaporation by a nearby O star has removed gas from the outer disk of a young low mass star (see also Balog et al. 2006; Balog et al. 2008).Comment: 11 pages, 3 figures. Accepted for publication to ApJ Letter

    Novel type of phase transition in a system of self-driven particles

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    A simple model with a novel type of dynamics is introduced in order to investigate the emergence of self-ordered motion in systems of particles with biologically motivated interaction. In our model particles are driven with a constant absolute velocity and at each time step assume the average direction of motion of the particles in their neighborhood with some random perturbation (η\eta) added. We present numerical evidence that this model results in a kinetic phase transition from no transport (zero average velocity, va=0| {\bf v}_a | =0) to finite net transport through spontaneous symmetry breaking of the rotational symmetry. The transition is continuous since va| {\bf v}_a | is found to scale as (ηcη)β(\eta_c-\eta)^\beta with β0.45\beta\simeq 0.45

    Spin-Peierls Dimerization of a s=1/2 Heisenberg Antiferromagnet on a Square Lattice

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    Dimerization of a spin-half Heisenberg antiferromagnet on a square lattice is investigated for several possible dimerized configurations, some of which are shown to have lower ground state energies than the others. In particular, the lattice deformations resulting in alternate stronger and weaker couplings along both the principal axes of a square lattice are shown to result in a larger gain in magnetic energy. In addition, a `columnar' configuration is shown to have a lower ground state energy and a faster increase in the energy gap parameter than a `staggered' configuration. The inclusion of unexpanded exchange coupling leads to a power law behaviour for the magnetic energy gain and energy gap, which is qualitatively different from that reported earlier. Instead of increasing as δx\delta ^{x}, the two quantities depend on δ\delta as δν/lnδ.\delta ^{\nu}/| \ln \delta | . This is true both in the near critical regime (0δ0.1)(0\leq \delta \leq 0.1) as well as in the far regime (0δ<1)(0\leq \delta <1). It is suggested that the unexpanded exchange coupling is as much a source of the logarithmic dependence as a correction due to the contribution of umklapp processes. Staggered magnetization is shown to follow the same δ\delta -dependence in all the configurations in the small δ\delta -regime, while for 0δ<10\leq \delta <1, it follows the power law δx\delta ^{x}.Comment: 12 pages, 7 Postscript figures, RevTex forma

    Rhenium oxyhalides: a showcase for anisotropic-triangular-lattice quantum antiferromagnets

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    The spin-1/2 Heisenberg antiferromagnet on an anisotropic triangular lattice (ATL) is an archetypal spin system hosting exotic quantum magnetism and dimensional crossover. However, the progress in experimental research on this field has been limited due to the scarcity of ideal model materials. Here, we show that rhenium oxyhalides A3A_{3}ReO5X2_{5}X_{2}, where spin-1/2 Re6+^{6+} ions form a layered structure of ATLs, allow for flexible chemical substitution in both cation A2+A^{2+} (AA = Ca, Sr, Ba, Pb) and anion XX^{-} (XX = Cl, Br) sites, leading to seven synthesizable compounds. By combining magnetic susceptibility and high-field magnetization measurements with theoretical calculations using the orthogonalized finite-temperature Lanczos method, we find that the anisotropy J/JJ'/J ranges from 0.25 to 0.45 depending on the chemical composition. Our findings demonstrate that A3A_{3}ReO5X2_{5}X_{2} is an excellent platform for realizing diverse effective spin Hamiltonians that differ in the strength of the anisotropy J/JJ'/J as well as the relevance of perturbation terms such as the Dzyaloshinskii-Moriya interaction and interlayer exchange coupling.Comment: 11 pages, 5 figures, SM: 4 pages, 2 figure

    The role of mothers-in-law in antenatal care decision-making in Nepal: a qualitative study

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    Background Antenatal care (ANC) has been recognised as a way to improve health outcomes for pregnant women and their babies. However, only 29% of pregnant women receive the recommended four antenatal visits in Nepal but reasons for such low utilisation are poorly understood. As in many countries of South Asia, mothers-in-law play a crucial role in the decisions around accessing health care facilities and providers. This paper aims to explore the mother-in-law’s role in (a) her daughter-in-law’s ANC uptake; and (b) the decision-making process about using ANC services in Nepal. Methods In-depth interviews were conducted with 30 purposively selected antenatal or postnatal mothers (half users, half non-users of ANC), 10 husbands and 10 mothers-in-law in two different (urban and rural) communities. Results Our findings suggest that mothers-in-law sometime have a positive influence, for example when encouraging women to seek ANC, but more often it is negative. Like many rural women of their generation, all mothers-in-law in this study were illiterate and most had not used ANC themselves. The main factors leading mothers-in-law not to support/ encourage ANC check ups were expectations regarding pregnant women fulfilling their household duties, perceptions that ANC was not beneficial based largely on their own past experiences, the scarcity of resources under their control and power relations between mothers-in-law and daughters-in-law. Individual knowledge and social class of the mothers-in-law of users and non-users differed significantly, which is likely to have had an effect on their perceptions of the benefits of ANC. Conclusion Mothers-in-law have a strong influence on the uptake of ANC in Nepal. Understanding their role is important if we are to design and target effective community-based health promotion interventions. Health promotion and educational interventions to improve the use of ANC should target women, husbands and family members, particularly mothers-in-law where they control access to family resources

    Operator Ordering Problem of the Nonrelativistic Chern-Simons Theory

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    The operator ordering problem due to the quantization or regularization ambiguity in the Chern-Simons theory exists. However, we show that this can be avoided if we require Galilei covariance of the nonrelativistic Abelian Chern-Simons theory even at the quantum level for the extended sources. The covariance can be recovered only by choosing some particular operator orderings for the generators of the Galilei group depending on the quantization ambiguities of the gaugemattergauge-matter commutation relation. We show that the desired ordering for the unusual prescription is not the same as the well-known normal ordering but still satisfies all the necessary conditions. Furthermore, we show that the equations of motion can be expressed in a similar form regardless of the regularization ambiguity. This suggests that the different regularization prescriptions do not change the physics. On the other hand, for the case of point sources the regularization prescription is uniquely determined, and only the orderings, which are equivalent to the usual one, are allowed.Comment: 18 page

    Universality in Bacterial Colonies

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    The emergent spatial patterns generated by growing bacterial colonies have been the focus of intense study in physics during the last twenty years. Both experimental and theoretical investigations have made possible a clear qualitative picture of the different structures that such colonies can exhibit, depending on the medium on which they are growing. However, there are relatively few quantitative descriptions of these patterns. In this paper, we use a mechanistically detailed simulation framework to measure the scaling exponents associated with the advancing fronts of bacterial colonies on hard agar substrata, aiming to discern the universality class to which the system belongs. We show that the universal behavior exhibited by the colonies can be much richer than previously reported, and we propose the possibility of up to four different sub-phases within the medium-to-high nutrient concentration regime. We hypothesize that the quenched disorder that characterizes one of these sub-phases is an emergent property of the growth and division of bacteria competing for limited space and nutrients.Comment: 12 pages, 5 figure

    A Neutral Polyampholyte in an ionic solution

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    The behavior of a neutral polyampholyte (PAPA) chain with NN monomers, in an ionic solution, is analyzed in the framework of the full Debye-Hu¨\ddot u ckel-Bjerrum-Flory (DHBjF)(DHBjF) theory. A PAPA chain, that in addition to the neutral monomers, also contains an equal number of positively and negatively charged monomers, is dissolved in an ionic solution. For \underline{high} concentrations of salt and at high temperatures, the PAPA exists in an extended state. As the temperature is decreased, the electrostatic energy becomes more relevant and at a T=TθT=T_{\theta} the system collapses into a dilute globular state, or microelectrolyte. This state contains a concentration of salt higher than the surrounding medium. As the temperature is decreased even further, association between the monomers of the polymer and the ions of the salt becomes relevant and there is a crossover from this globular state to a low temperature extended state. For \underline{low} densities of salt, the system is collapsed for almost all temperatures and exhibits a first-order phase transition to an extended state at an unphysical low temperature.Comment: 10 pages, Revtex with epsf, 9 Postscript figures. Submitted to PR
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